Evaluating the toxicity of chemical substances in the products we use is a key component of a management regime to protect human health and the environment. Advances in the science and technology of toxicity testing hold out the promise of more efficient, prompt, accurate and cost-effective testing methods. As the media, the public, and various stakeholder groups raise concerns about the safety of everyday items, chemicals policy in the U.S. is coming under scrutiny. Other countries are revising or have already revised their chemical regulations. This briefing will look at how improvements in understanding and evaluating toxicity can be utilized, and what implementation challenges must be overcome, in order to effectively modernize the management of toxic chemicals in the U.S.
Contact Science & the Congress Briefing Series

ACS Science & the Congress Project,
The Society for Risk Analysis, and
President, Risk Science & Management, LLC
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Daniel Krewski Director, McLaughlin Centre for Population Risk Assessment University of Ottawa Presentation Slides Bio │Email | |
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James Bus Director, External Technology The Dow Chemical Company Presentation Slides Bio │Email | http://acswebcontent.acs.org/flv/SC_Briefings/Dec_10_2009/Bus_Dec10_09.flv |
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Melvin Andersen Director, Program in Chemical Safety Sciences The Hamner Institutes in Health Sciences Presentation Slides Bio │Email | http://acswebcontent.acs.org/flv/SC_Briefings/Dec_10_2009/Anderson_Dec10_09.flv |
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Steven Bradbury Deputy Director, Office of Pesticide Programs The U.S. Environmental Protection Agency Presentation Slides Bio │Email | http://acswebcontent.acs.org/flv/SC_Briefings/Dec_10_2009/Bradbury_Dec10_09.flv |
“Toxicity Testing in the 21st Century,”Risk Analysis, Vol. 29, No. 4, 2009
“Forum Series, Part I: Toxicity Testing in the 21st Century: Bringing the Vision to Life,”Toxicological Sciences 107(2), 324-330 (2009)
“Forum Series, Part VIII: Toxicity Testing in the 21st Century: A View from the Chemical Industry,”Toxicological Sciences 112(2), 297-302 (2009)
“Toxicity Testing in the 21st Century: Better Results, Less Use of Animals,”The Environmental Forum, March/April 2008
“Toxicity Testing in the 21st Century: A Vision and a Strategy,” 2007
Symposium on Toxicity Pathway-Based Risk Assessment: Preparing for Paradigm Change
“The Toxic Substances Control Act (TSCA): Implementation and New Challenges,” CRS RL34118, updated July 28, 2009
“The Toxic Substances Control Act: A Summary of the Act and Its Major Requirements,” CRS RL31905, updated March 3, 2009
Strategic Direction for New Pesticide Testing and Assessment Approaches
The U.S. Environmental Protection Agency's Strategic Plan for Evaluating the Toxicity of Chemicals
EPA National Center for Computational Toxicology – Basic Information
Memorandum of Understanding between EPA and NIH
National Institute of Environmental Health Sciences
Office of the National Toxicology Program
“Recasting the U.S. Chemical Law,”C&EN, October 5, 2009
“Revisiting Chemical Control Law: Congress scrutinizes Toxic substances control act with eye toward reforming the statute,” C&EN, March 9, 2009
“Managing Chemicals Worldwide: UN work is a top issue at industry gathering on chemical regulation,” C&EN, April 20, 2009
“Next-Generation Risk Assessment,”C&EN, June 22, 2009
“Cost of REACH Underestimated: EU’s chemical testing program may require millions more animals and Euros than expected,” C&EN. August 26, 2009.
“Revision Looms for U.S. Chemical Law: EPA’s Struggle to get toxicity data increases the likelihood of congressional action ,” C&EN, June 9, 2008
“Toxicity Testing Without Animals,”C&EN, May 27, 2009