Haplophytine is an insecticidal alkaloid that has been used since Aztec times. It was first isolated from the Mexican plant Haplophyton cimicidum by H. R. Snyder and co-workers in 1951. Its structure was determined by a research team led by P. Yates in 1967; but its total synthesis (in 29 steps!) wasn’t achieved until T. Fukuyama, H. Tokuyama, and colleagues reported it this year.
More about this molecule from CAS.
Log In